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Plegridy (peginterferon beta) is a disease modifying treatment (DMT) for relapsing remitting multiple sclerosis that is given as an injection every two weeks. Share your experiences of Plegridy or find out how others have found the treatment.

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@abi93

24 Mar 2025 08:25 EditedLast reply 24 Mar 2025 17:59

Plegridy

I've recently been diagnosed with MS and am due to start plegridy but feeling quite nervous after reading about all the side effects 😫are there any plegridy users who can tell me a little about their experience on it? Thank you! X

First posted on the Shift.ms app

@JoMaccy24

13 May 2022 15:34 EditedLast reply 18 Mar 2025 18:47

Bad Reaction to Plegridy / Avonex Experiences

Hi, Hoping to get some advice about some recent reactions I've had to taking Plegridy. The last two times I've taken the injection I've had a really intense neurological 'episode' a few hours afterwards: sudden drop in body temperature (33.8 degrees on the thermometer) whole body shaking because of...

@Jaqshell

9 Dec 2023 16:41Last reply 30 May 2024 08:10

Plegridy

Does anyone take plegridy?

Preston, United Kingdom

@Cmaxy

22 Sep 2023 04:58Last reply 29 Nov 2023 13:30

How is anymore getting on with plegridy?

Good morning MS community 🤗. I was diagnosed in July with relapsing ms and have had it for four years before diagnosis. I am due to start my injections once the nurse has visited to show me correctly how to do the injection. I had worries about medication (family all have died of liver cancer or p...

Kettering, United Kingdom

@Kimberley87

11 Sep 2023 18:00Last reply 13 Sep 2023 00:34

To Plegridy or not to Plegridy

Hello! First experience of DMTs. My MS team have just prescribed Plegridy. What’s everyone’s experience on this one? Open to all the good, bad and ugly feedback. Thanks in advance!

Northampton, UK

@RebeccaR07

9 Jan 2022 05:17Last reply 31 Jul 2023 18:33

PLEGRIDY Injections

Hi.. I’m currently on plegridy injection, does anyone else have varied side effects every time you inject (fortnightly). Some weeks I’m fine and other weeks I have flu-like reactions and massive headaches for days and it wipes me out and I’m bedbound because of the side effects. Thank you

@Akj12

11 Feb 2023 15:03Last reply 3 May 2023 16:17

Plegridy Treatment

Hey everyone, im having my Treatment changed from Avonex to Plegridy and i was wondering if anyone has ever done that shift before and if you encountered any horrible side effect.. im changing treatments because im currently on weekly injections and the injection sites are really painful so my MS nu...

@Rolo

6 Mar 2023 17:13Last reply 12 Mar 2023 09:52

Plegridy

Hi I am due to start on Plegridy this month how have others found it ? Sorry if it’s a silly question just trying to get my head around it all and feeling a bit overwhelmed!

@Kimberley11

24 Feb 2023 13:56 Edited

Plegridy and knee pain?!?

Hi, I’ve just started Plegridy (began in January and built up to full dose now) and I’ve noticed injection site reactions which is annoying but I was expecting. I’ve also noticed quite severe pains in my knees at times. It seems like it might be linked to the Plegridy as it started shortly afterward...

Plymouth, United Kingdom

@Sophiemini

13 Dec 2022 14:26Last reply 16 Dec 2022 06:49

Plegridy or ms headache?

Hi, relatively newly diagnosed (April this year). Has anyone else experienced an ongoing splitting headache from either plegridy or ms? I'm trying to figure out what is causing it but don't know where to start, not hoping someone else has has similar experience, but if you have I'd like to hear abou...

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