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Vitamins & Fatigue

Does anyone know a good multivitamin to help fight fatigue? One that really works and gives you energy? I know vitamin D is supposed to help, is there anything else? This fatigue has got to go.

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@Tia

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Saw this and wanted to share : A microscopic discovery may quietly change how multiple sclerosis drugs are designed and why their side effects happen at all.For years, doctors have relied on immune-modulating drugs to slow multiple sclerosis (MS), even though many come with troubling side effects affecting the heart, lungs, or nervous system. Now, scientists from Weill Cornell Medicine and Memorial Sloan Kettering Cancer Center have uncovered why some of those side effects occur and how future drugs could avoid them.Using ultra-high-resolution cryo-electron microscopy, researchers mapped the exact molecular structure of siponimod, a next-generation MS drug, as it binds to its immune target: the S1P1 receptor. This receptor acts like a gatekeeper, controlling whether aggressive immune cells escape lymph nodes and attack nerve insulation in the brain and spinal cord.The breakthrough? Scientists discovered precisely which parts of the drug help it hit the right receptor and which subtle features cause it to accidentally bind to similar receptors linked to abnormal heart rhythms and other side effects. With this structural “blueprint,” future MS drugs could be engineered to lock onto the correct target more tightly while avoiding the rest.Even more intriguing, the study reveals how nearly identical natural lipids can behave completely differently inside the body, shaping immune, brain, and lung function. That insight may ripple beyond MS, influencing treatments for lupus, psoriasis, inflammatory bowel disease and even lung disease.If medicines could be redesigned at the molecular level to spare the rest of the body, would you accept stronger immune control with fewer side effects?

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@JamesYates

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I’ve been on this platform for multiple years, just not usually one to post. I felt the need to break that for a useful couple of tips I’ve found through multiple practice attempts. This post is for heading off muscle spasms in both thr arms and legs. Though these tips work for me, I don’t want to...

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@Miraa

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Please any advice

I have been feeling nauseous for 2 years now I am on ant sickness medication but they seem to not help as they use to , is this normal with MS ? I struggle to get out off the bed sometimes that’s how bad me nauseous gets ,

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@stavy917

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Gabapentin

Hi I’m on amatriptaline at the moment but it’s making me feel like an emotional zombie so I’ve asked for gabapentin can I ask if this is any good if anyone is on it ?

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@Sanchez85

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Weird feeling in leg

I started getting this feeling under on my lower leg like if it’s being squeezed or maybe pressure. This is second time I’ve felt it. First time lasted couple days then went away. Here I am again with it. Anyone else feel this?

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@Sarah52

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Change of meds

My DR has reduced my pregabalin tablets too quickly I went in to a crisis and everything was making me catastrophise everything making it so hard on spasms and tears. I can't focus, contrate on anything and feel like I have too much going on in my mind and felt like I was losing my life. This was ...

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@DanR

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MS and Bells Palsy?!

So, a year and 3 months down the line being diagnosed with “inactive MS” being put on Avonex to then be taken off it 4 months later as It made me very ill and since being off treatment I have had 5 new lesions and all types of new relapses (fizzy feeling in my spine, MS hug, constant tingling) I now...