#plegridy - Shift.ms

Plegridy (peginterferon beta) is a disease modifying treatment (DMT) for relapsing remitting multiple sclerosis that is given as an injection every two weeks. Share your experiences of Plegridy or find out how others have found the treatment.

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@Michellejohn35

2 Jun 2025 18:17

ecently had my MRI results and (as I kinda suspected after a rough few months) had new lesions.I'm currently on Plegridy (moved from Tecfidera as I'm JCV positive and my lymphocytes lowered a lot). Tecfidera worked ok for me, but Plegridy obviously hasn't been as effective. Due to the hard few months I've really isolated myself from people (some I'm unsure even how to reach out to again now) and live alone alone some of the time when my four children are at their mum's. Positive news is, they've mentioned Ocrevus and Kesimpta, which are obviously higher efficacy treatments. Could I ask for any advice people have around these DMTs, please? If you've seen me ask on Facebook or Instagram, then feel free to ignore and not repeat yourself.

First posted on the Shift.ms app

@MK24

2 Jun 2025 17:22Last reply 4 Jun 2025 11:34

Ocrevus or Kesimpta

I recently had my MRI results and (as I kinda suspected after a rough few months) had new lesions. I'm currently on Plegridy (moved from Tecfidera as I'm JCV positive and my lymphocytes lowered a lot). Tecfidera worked ok for me, but Plegridy obviously hasn't been as effective. Due to the hard fe...

, United Kingdom

First posted on the Shift.ms app

@tash221993

12 May 2025 19:10Last reply 15 May 2025 19:04

Hi everyone! I have been recently diagnosed with RRMS. My nurse has advised that I start a DMT - either Avonex or Plegridy. Is anybody on these or does anybody have any advice on which one I should go for? Thank you in advance

First posted on the Shift.ms app

@erika

19 Apr 2025 09:59Last reply 20 Apr 2025 19:36

Ocrevus and colds 😩

I’ve been on ocrevus for a year previous to this I was on Plegridy for 5 years, since starting the infusions I get every cold flu Covid whatever is going, I know this is a side effect has anyone else had this? Does it improve? Should I consider alternatives? I’m a nurse I am exposed to lots of bugs ...

Stafford, United Kingdom

@abi93

24 Mar 2025 08:25 EditedLast reply 24 Mar 2025 17:59

Plegridy

I've recently been diagnosed with MS and am due to start plegridy but feeling quite nervous after reading about all the side effects 😫are there any plegridy users who can tell me a little about their experience on it? Thank you! X

First posted on the Shift.ms app

@melaniejane

2 Mar 2025 12:04Last reply 18 May 2025 18:02

MS & What to eat...

Hello everyone. Context, I'm switching from Plegridy to Tecfidera shortly and advise seems to indicate making sure I eat properly when taking this is key to limiting side effect. So question - any MS and 'what to eat' (I hate the word diet!) tips. Various medics have said Mediterranean diet and I've...

First posted on the Shift.ms app

@Victoria1971

18 Feb 2025 12:02

Started Brabio today

So after a 6 week break following side effects from Plegridy, I have had my first dose of Brabio today. I’m really hoping not to have any side effects as am hoping to go back to work soon. Interested to hear how other people are getting on with Brabio 😊

First posted on the Shift.ms app

@Jodavies77

16 Feb 2025 12:35Last reply 21 Feb 2025 19:42

Migraines

Anyone have migraines associated with ms, my ms started with cluster migraines leading onto blindness they say migraines are not anything to do with ms. However when I started plegridy ,(dmt,) my migraines stopped. Last year I had a flare up and boom withing a week.migraines are back now I'm on suma...

First posted on the Shift.ms app

@Markae

30 Jan 2025 10:25

2nd part ocrevus

2nd of 2 then be done till July. Apart from extreme fatigue after infusion and a little under the weather this seems a good fit with little to no side affects better then tec and pleguidy which I have been on with awful side affects and injection site infection on the latter. Arm still aches from th...

First posted on the Shift.ms app

@Marigold_River

18 Dec 2024 22:24

Injection

So I've been taking injections since 2021 first plegridy now Kesimpta No bleeding First blood today 😂 this time I've injected myself and drew blood 😅 I don't feel like I did anything different, top of the thigh. Though this is the first time I've been given the cotton swabs and wipes along wit...

Sheffield, United Kingdom

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