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This months People's Hot Topic is 'Repurposing of Drugs'. Please follow the link below to view a video introducing this topic. https://shift.ms/2013/09/peoples-hot-topic-repurposing-of-drugs/ We're keen to hear what you want to know. Anything at all - please share you question. There is no such t...

SIZOMUS is investigating the first proper adjunct (add-in) drug for MS. It is as well as your DMT, not instead of. It isn't a new compound but it is repurposing an existing drug with a well-established safety profile so I don't feel like a guinea pig for an unknown drug. https://youtube.com/shorts/...

Bonjour (Rodney?), - BoJo HAS IT - really, you're not dreaming. I hope Rishi doesn't. Far from perfect but an order of magnitude better than the Buffoon. IMHO. - If you haven't seen the latest news our esteemed leader, the Tousled Haired Buffon, has tested positive for Covid-19. Whilst I wouldn't t...

The poll has spoken - and you all chose Repurposing Drugs for the People's Hot Topic this time around. You can find out a bit more about the subject and ask your own questions here https://shift.ms/2013/10/ask-your-questions-the-peoples-hot-topic/ And we will get your questions answered by Prof G...

The poll has spoken - and you all chose Repurposing Drugs for the People's Hot Topic this time around. You can find out a bit more about the subject and ask your own questions here https://shift.ms/2013/10/ask-your-questions-the-peoples-hot-topic/ And we will get your questions answered by Prof G...

Advice from María Sabina, Mexican healer and poet - “Heal yourself with the light of the sun and the rays of the moon. With the sound of the river and the waterfall. With the swaying of the sea and the fluttering of birds. Heal yourself with mint, neem, and eucalyptus. Sweeten with lavender, ro...

Is anyone here taking Statins? Either as part of the MS-STAT trial ( https://www.nihr.ac.uk/documents/case-studies/ms-stat-impact-case-study/21482 ) or just because - of simvastatin 80mg or any other dose of atorvastatin for that matter? I have persuaded my GP to give me atorvastatin (one of the s...

Simvastatin is one of the Statins, the cholesterol lowering drugs, that are being looked at in MS. This is a London hospital running it at several centres around the UK. I have no interest or concern in this, just reposting it. SPMS only. https://www.ucl.ac.uk/ion/research/centres/queen-square...

If you are Secondary Progressive MS (SPMS), between 20 and 65 with an EDSS of between 4.0 and 6.5, then this trial may be for you. Details here :- https://www.ucl.ac.uk/ion/research/centres/queen-square-multiple-sclerosis-centre/ms-clinical-trials/ms-stat2-trial

Hi all i have a question for you: If you have to safe two drugs/supplents what would they be? in my case I would take: vitamin D (only because i had a densitometry and my bones are not getting any worse), magnesium chloride ( it seems to ease spasciticy) Maybe: fingolimod, lipoic acid and simvas...

Currently i'm on Copaxone (DMD) and a 100mg Amitriptyline and Tramadol at night to help me rest from the Neurological Pain that is like burning fire and tingling, have never had any relief from this pain since being diagnosed in 2015 and it is steadily increasing around my body. Any pain relief woul...

Hi all I was wondering if any of you with spms is on statins (simvastatin) and if they have any benefit on you. I look forward to heating from you. Xxx

Hi All, just picked up 2 months worth of Simvastatin 80mg form my Doctors, my Neuro suggested it but it is an off label so to speak prescription. Anyone had any experience with it? The muscle atrophy, the most serious of the possible side effects is concerning! Barry

Re-purposing drugs is one of the ways we can accelerate the drug development. Currently any effective treatment would take at least 15-20 years in clinical trials. That would be much too late for us folk and more for people with progressive disease. Pharma obviously won't invest in off patent drugs...