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Research

https://multiplesclerosisnewstoday.com/news-posts/2025/06/25/3-progressive-ms-patients-see-lowered-disability-car-t-cell-therapy/

First posted on the Shift.ms app

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Research

https://ms-uk.org/news/subcutaneous-ocrevus-shows-almost-complete-suppression-of-relapses/?fbclid=IwZXh0bgNhZW0CMTEAAR06WI-TXPt4ILOgDa2PLewcN71DmlTwvNKRfvSkCyWje46uHyKv1IQILOo_aem_AQkxdc6Qrc7BEbApcrsWobajxVRnvqwMkghvBpRsPI8cJx6HBBzx8xpLyvoSZRmZRORwau9grT7p9cWJIRxV6Fi6

Newbridge, United Kingdom

Unpublished

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Research

Hi everyone. I am a Doctoral student and am looking for volunteers to fill in a short survey for my work.. is anyone interested?

Evesham, UK

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research

Hi guys I have MS and just come across this site, and I think you can help me. I am training as a counsellor. I am doing research to see who has used counselling? What organisation it was etc? How did you get referred?

Sutton Coldfield, United Kingdom

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Research

https://www.mssociety.org.uk/research/latest-research/latest-research-news-and-blogs/new-research-identifies-which-type-nerve-cells-are-lost-ms

Falkirk, Scotland, United Kingdom

Research

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Research

My optimism is growing and growing in the belief that one day there will be significant treatment which would benefit all of us, perhaps even sooner than we expected, so much funding has gone into Multiple Sclerosis and I am starting to gently raise my head day-by-day. I wish you all the very best!

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For those of you who have been living with MS for a while, how do you handle situations where people know about your diagnosis and start sharing opinions or unsolicited comments about it? How do you remain calm and composed in those moments?….. I what to say… if you just the research !!….

First posted on the Shift.ms app

@Flores_Doramis_Jr_

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Has anyone tried stem cell research I’ve heard positive things

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I’m on Avonex for 6+ years. Have no issue but would like to change. Dr has made several suggestions but I’m confused with all the data. Here are a few suggestions: Kesemta, Malvenclad or Zeposia. I’ve done all the research but now I’m more confused than ever. What’s everyone on?

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Saw this and wanted to share : A microscopic discovery may quietly change how multiple sclerosis drugs are designed and why their side effects happen at all.For years, doctors have relied on immune-modulating drugs to slow multiple sclerosis (MS), even though many come with troubling side effects affecting the heart, lungs, or nervous system. Now, scientists from Weill Cornell Medicine and Memorial Sloan Kettering Cancer Center have uncovered why some of those side effects occur and how future drugs could avoid them.Using ultra-high-resolution cryo-electron microscopy, researchers mapped the exact molecular structure of siponimod, a next-generation MS drug, as it binds to its immune target: the S1P1 receptor. This receptor acts like a gatekeeper, controlling whether aggressive immune cells escape lymph nodes and attack nerve insulation in the brain and spinal cord.The breakthrough? Scientists discovered precisely which parts of the drug help it hit the right receptor and which subtle features cause it to accidentally bind to similar receptors linked to abnormal heart rhythms and other side effects. With this structural “blueprint,” future MS drugs could be engineered to lock onto the correct target more tightly while avoiding the rest.Even more intriguing, the study reveals how nearly identical natural lipids can behave completely differently inside the body, shaping immune, brain, and lung function. That insight may ripple beyond MS, influencing treatments for lupus, psoriasis, inflammatory bowel disease and even lung disease.If medicines could be redesigned at the molecular level to spare the rest of the body, would you accept stronger immune control with fewer side effects?

First posted on the Shift.ms app