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Tecfidera (dimethyl fumarate, BG-12) is a disease modifying treatment (DMT) for active relapsing remitting multiple sclerosis. Tecfidera is a pill which is taken twice a day; trials have shown it reduces the number of relapses by around 50% compared to a placebo.Read all about the pros and cons of Tecfidera MS treatment from other MSers, or get involved by asking a question.

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@wanttorun

13 Jun 2025 15:25Last reply 14 Jun 2025 07:03

Random question about steroids

Hi, I was just wondering how you decide when to take steroids. I have RRMS and am on tecfidera, due to change to Kesimpta in August. For the most part my MS has been stable and more of a label than anything else. However last week I woke up with a lightly numb face, over the week I have regai...

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@Michellejohn35

2 Jun 2025 18:17

ecently had my MRI results and (as I kinda suspected after a rough few months) had new lesions.I'm currently on Plegridy (moved from Tecfidera as I'm JCV positive and my lymphocytes lowered a lot). Tecfidera worked ok for me, but Plegridy obviously hasn't been as effective. Due to the hard few months I've really isolated myself from people (some I'm unsure even how to reach out to again now) and live alone alone some of the time when my four children are at their mum's. Positive news is, they've mentioned Ocrevus and Kesimpta, which are obviously higher efficacy treatments. Could I ask for any advice people have around these DMTs, please? If you've seen me ask on Facebook or Instagram, then feel free to ignore and not repeat yourself.

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@MK24

2 Jun 2025 17:22Last reply 4 Jun 2025 11:34

Ocrevus or Kesimpta

I recently had my MRI results and (as I kinda suspected after a rough few months) had new lesions. I'm currently on Plegridy (moved from Tecfidera as I'm JCV positive and my lymphocytes lowered a lot). Tecfidera worked ok for me, but Plegridy obviously hasn't been as effective. Due to the hard fe...

, United Kingdom

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@Underdog

27 May 2025 13:02

Being "Switched" to cheaper drugs

https://www.independent.co.uk/news/health/ms-tyruko-tysabri-drug-side-effects-nhs-b2754395.html How widespread is this and is it only Tysabri and (from what I read on another site) possibly Tecfidera affected at the moment? I would hate to be pulled away from Kesimpta and onto a "simillar" drug wh...

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@Nina18

23 May 2025 05:45Last reply 23 May 2025 21:48

Switching from Ocrevus to Kesimpta

Well I think that this has been the shortest time frame I have ever been on ANY! type of medication. I was diagnosed in March of this year with heart palpitations due to the medication. I gave it fair shot and I just can not deal with the anxiety attacks feeling, the off beat of my heart once in aw...

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@Spiderhack

12 May 2025 13:58Last reply 13 May 2025 01:33

Normal medication

Hello fellow MS people I am currently on DImethyl fumarate (Tecfidera) and whilst it’s done its job as far as I am aware. Are there any other natural Meds people recommend and if so where you get them from ? I am in the UK I appreciate exercise is a great one which I do but sometimes I am too tir...

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@Chrissykain

11 May 2025 02:39Last reply 11 May 2025 23:48

cladribine

So I was dx 2009. Copaxone nearly killed me. Tecfidera caused me severe acne. I lost the feeling from my neck down September last year and finally had an mri in April. I broke my shoulder in October (slipped on holiday in Bulgaria) had surgery there and had plates and pins , they flew me home too ...

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@SennaWaiIChan

25 Apr 2025 22:56Last reply 26 Apr 2025 12:16

Advise

Hi everyone, I’ve been diagnosed with RRMS for four years now and have been on Tecfidera since the beginning. My latest MRI showed a bit of progression, and my neurologist has suggested switching to Siponimod. I was wondering if anyone here has any personal experience with this medication – how have...

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@Lightning87

15 Apr 2025 19:28Last reply 15 Apr 2025 21:40

Ocrevus - your experiences

Hello! I was diagnosed in June 2018 and was on Tecfidera for 6 years before my Neuro advised I would require to come off the DMT as my lymphocytes were below 0.5 for longer than 6 months. I had to go ’cold turkey’ until my lymphocytes went back up to 0.8 which they just have, thankfully. They hav...

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@Jillianleigh16

3 Apr 2025 19:30 EditedLast reply 14 Apr 2025 14:43

Tecfidera (dimethyl fumerate)

Has anyone taken this Medication? I took my first dose Last Friday and had a horrible reaction of severe flushing, high BP and HR I was sent to ER from work. Any advice or similar reactions? Update: I have been completely stopped on the Tecfidera. I will be switching neurologists due to mine movin...

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