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Charity Number: 1117194 (England and Wales)

Registered Company: 06000961

Registered address:
Shift.ms, Platform, New Station Street, LS1 4JB, United Kingdom

London office:
Shift.ms, Somerset House, Strand, West Goods Entrance, London WC2R 1LA, United Kingdom

ยฉ2025 Shift.ms

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There are now 11 licensed treatments for multiple sclerosis, commonly known as DMTs (disease modifying therapies). These are available for people with relapsing remitting multiple sclerosis and range from Tysabri, Lemtrada, oral therapies, to copaxone and the interferons. Speak with those living with MS to find out first hand what it is like to be on a particular treatment, or, if you have a question for an expert, check out our MS Reporters videos. DMTs are not a cure for MS, but they can have impacts on relapse rates, disease progression, MRI activity and long term brain health.

Topics

  • Aubagio
  • Avonex
  • Betaferon
  • Copaxone
  • Extavia
  • Gilenya
  • Lemtrada
  • Ocrevus
  • Plegridy
  • Rebif
  • Tecfidera
  • Tysabri
  • Unlicensed
  • Which DMT
  • HSCT
  • Browse all
Sort approximately 12434 results by
Recent activityNewest posts

@BrittanyOwen 

13 Jun 2025 16:11Last reply 13 Jun 2025 17:40

BrittanyOwen

What do i do??

I have been on the steroids for almost 2 weeks now, and it seems like im getting worse. EVERYTHING is sooo tight, im holding a bunch of fluid in my mid section from the meds, im sore, im exhausted, and more places are going numb. I go to my first clinical appt on Monday, but im getting very upset. I...
First posted on the Shift.ms app
2

@karzan 

12 Jun 2025 21:12Last reply 12 Jun 2025 21:23

karzan

Attack?

Dose anybody get another attack after treatment?
First posted on the Shift.ms app
2

@FelixKai 

11 Jun 2025 09:38Last reply 12 Jun 2025 16:30

FelixKai

Any advice?

I've seen stories about other people who have gotten diagnosed at a young age, but do any of you have advice for it? I've spent the last 5 years going from Dr to Dr in multiple different states to find out what was wrong as my health was rapidly declining and only recently (last August) found out I ...
First posted on the Shift.ms app
3

@stavy917 

10 Jun 2025 19:29Last reply 11 Jun 2025 15:22

stavy917

Hi just got diagnosed yesterday and was given treatment options I went for the dimethyl fumarate anybody know if itโ€™s any good as Iโ€™m completely new to all this and a little worried ๐Ÿซค

First posted on the Shift.ms app
18

@Charlotte85 

7 Jun 2025 21:28Last reply 10 Jun 2025 04:21

Charlotte85

Any help is appreciated

Hi everyone. I hope your well. I just need somewhere to turn to. Ive left my husband...his fault...cant be faithful and other things I won't get into but im surely falling apart. Living in a hotel with my 2 kids one is 4 and one is 15 and autistic. Housing are moving me 45mins away from the school a...
First posted on the Shift.ms app
9

@BrittanyOwen 

6 Jun 2025 20:20Last reply 7 Jun 2025 22:55

BrittanyOwen

Scared, and looking for guidance.

I have always felt, off. My entire life. A few weeks ago, I woke up to numbness on the left side of my body. Over the course of a week, and numerous hospitals turning me away, the numbness progressed from part of my head, to the entirety of my left side down to my foot and excruciating pain in the b...
First posted on the Shift.ms app
15

@Leah89 

6 Jun 2025 07:45 EditedLast reply 8 Jun 2025 13:23

Leah89

Hi, I got diagnosed in January and started on medication after a very long wait about a month ago, unfortunately I had a very severe reaction to copaxone....I need to start another treatment however it's limited what I can take due to the fact me and my partner are trying for another baby just wondering what anyone else is or has taken whilst trying to conceive? My ms nurse keeps trying to push the infusion but due to the severe reaction I had after only 4 jabs I don't fancy 6 months worth at a time going into my body. Thanks for reading

First posted on the Shift.ms app
11

@jenine 

4 Jun 2025 18:22Last reply 5 Jun 2025 21:30

jenine

Infusions at home?

Has anyone gotten an ocrevus infusion at home? I did my first 2 treatments of 300mg with no problems or reactions. Insurance wonโ€™t cover me getting my next (600mg) at the hospital so they recommended at home.
First posted on the Shift.ms app
6
Unpublished

@Michellejohn35 

2 Jun 2025 18:17

Michellejohn35

ecently had my MRI results and (as I kinda suspected after a rough few months) had new lesions.I'm currently on Plegridy (moved from Tecfidera as I'm JCV positive and my lymphocytes lowered a lot). Tecfidera worked ok for me, but Plegridy obviously hasn't been as effective. Due to the hard few months I've really isolated myself from people (some I'm unsure even how to reach out to again now) and live alone alone some of the time when my four children are at their mum's. Positive news is, they've mentioned Ocrevus and Kesimpta, which are obviously higher efficacy treatments. Could I ask for any advice people have around these DMTs, please? If you've seen me ask on Facebook or Instagram, then feel free to ignore and not repeat yourself.

First posted on the Shift.ms app

@MK24 

2 Jun 2025 17:22Last reply 4 Jun 2025 11:34

MK24

Ocrevus or Kesimpta

I recently had my MRI results and (as I kinda suspected after a rough few months) had new lesions. I'm currently on Plegridy (moved from Tecfidera as I'm JCV positive and my lymphocytes lowered a lot). Tecfidera worked ok for me, but Plegridy obviously hasn't been as effective. Due to the hard fe...
, United Kingdom
First posted on the Shift.ms app
15
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