#mstrigger - Shift.ms

Last reply

MS trigger

Does anyone believe that severe trauma triggered their MS? I had this just before my symptoms started and sense this could have caused it, no medical evidence obviously but just my view.

First posted on the Shift.ms app

63

@MelissaCook

EditedLast reply

Nothing takes me down with MS faster than missing my sleep. I can usually do one night of fewer than eight hours, but two in a row? Last night I was WIDE-eyed and worried. A bout of food poisoning wreaked havoc on my night which I could typically manage, but not two nights in a row. The night before...

7

@tosh

Last reply

Result of a fall

Good morning. I'm new here and I'm looking for info. I fell several weeks ago and ended up with a minor concussion. Since then I've had nausea in the back of my throat every time I eat or drink. It's the feeling that you're gonna be sick but after a few minutes it goes away. My GP says that the...

2

@PumaPie

Last reply

NIHNational Institutes of HealthTurning Discovery Into HealthMENU< News & EventsMarch 27, 2018Gut microbe drives autoimmunityAt a Glance• Scientists found evidence that a certain gut microbe can trigger autoimmune disease in mice that are prone to such disease and identified the same microbe inpeople with autoimmune diseases.• The results suggest new avenues. At a Glance• Scientists found evidence that a certain gut microbe can trigger autoimmune disease in mice thatare prone to such disease and identified the same microbe inpeople with autoimmune diseases.• The results suggest new avenues for treating debilitating and potentially lethal autoimmune diseases. The lining of the intestine forms a barrier that is crucial to containing gut microbes. If the lining is breached and a gut microbe is able to get into the bloodstream and nearby organs, it can cause disease. Despite the fact that the body has many ways to prevent the breach, microbes sometimes get through.Previous studies have linked certain gut microbes to autoimmune disease, in which the immune system mistakenly attacks the body's own tissues.

First posted on the Shift.ms app

3

@PumaPie

NIHNational Institutes of HealthTurning Discovery Into HealthMENU< News & EventsMarch 27, 2018Gut microbe drives autoimmunityAt a Glance• Scientists found evidence that a certain gut microbe can trigger autoimmune disease in mice that are prone to such disease and identified the same microbe inpeople with autoimmune diseases.• The results suggest new avenues At a Glance• Scientists found evidence that a certain gut microbe can trigger autoimmune disease in mice thatare prone to such disease and identified the same microbe inpeople with autoimmune diseases.• The results suggest new avenues for treating debilitating and potentially lethal autoimmune diseases. The bacterium E. gallinarum (shown in orange) was found in liver tissue.Martin Kriegel lab, YaleThe human gut harbors a complex community of microbes that affect many aspects of our health. Known as the gut microbiota, these bacteria help with metabolism and maintaining a healthy immune system.The lining of the intestine forms a barrier that is crucial to containing gut microbes. If the lining is breached and a gut microbe is able to get into the bloodstream and nearby organs, it can cause disease. Despite the fact that the body has many ways to prevent the breach, microbes sometimes get through.Previous studies have linked certain gut microbes to autoimmune disease, in which the immune system mistakenly attacks the body's own tissues. A team led by Dr. Martin Kriegel at Yale investigated whether microbes breaching the gut barrier were involved in autoimmune disease. Their study was funded in part by NIH's National Institute of Allergy and Infectious Diseases (NIAID), National Institute of Diabetes. and National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS).Results appeared in Science on March 9, 2018.The researchers first tested how mice predisposed to autoimmune disease were affected by antibiotic treatment. In untreated mice, they found bacteria in nearby lymph nodes and the liver at 16 weeks of age, and also in the spleen 2 weeks later. Mice treated with the antibiotics vancomycin or ampicillin had this deadly growth suppressed.Analysis of cultures from nearby lymph nodes, liver, and spleen revealed the presence of a bacterium called Enterococcus gallinarum.When germ-free mice were colonized by E. gallinarum, the bacteria disrupted the gut barrier, moved into the lymph nodes and liver, and triggered an autoimmune response.To test whether depleting E. gallinarum alone could blunt autoimmune responses, the team developed vaccines using heat-killed bacteria.Vaccinating the prone mice against E. gallinarum, but not against two other gu microbes, reduced autoimmune responses6:30 Mspecific treatment can halt autoimmune responses without suppressing the entire immune system, which can have serious side effects.Finally, the researchers examined liver biopsies from people with autoimmune diseases. They found E. gallinarum in liver biopsies from three people with systemic lupus erythematosus, an autoimmune disease that can damage tissues all over the body. Similarly, the scientists foundE. gallinarum in liver biopsies from most people tested who had autoimmune liver disease.Biopsies from healthy liver transplant donors did not have the microbe.Taken together, these findings show that, in those who are prone, E. gallinarum can move through the gut barrier and into other organs to drive autoimmune responses. The resultssuggest new approaches to developing therapies for autoimmune diseases."The vaccine against E. gallinarum was a specific approach, as vaccinations against other bacteria we investigated did not pre mortality and autoimmunity," Kriegel saysapproaches such as vaccination are promising ways to improve the lives of patients with autoimmune disease."- by Harrison Wein, Ph.D.Related Links• Blocking Stomach Acid May PromoteChronic Liver Disease• Changing Gut Bacteria in Crohn's Disease• Infant Gut Microbes Linked to Allergy, Asthma Risk• Food Additives Alter Gut Microbes, Cause Diseases in Mice• Diet Affects Autoinflammatory Disease ViaGut Microbes• Gut Microbes Linked to RheumatoidArthritis• Your Microbes and You: The Good, Bad

First posted on the Shift.ms app

@PumaPie

Last reply

Bacteria in the gut have been implicated in autoimmune diseases, like lupus, that don't primarily affect the gastrointestinal system. But how those bacteria affect the human immune system remains unclear.In a new study, Yale researchers show how a gut bacterium called Enterococcus gallinarum can travel outside of the gastrointestinal system and trigger an autoimmune response. The findings, researchers say, may inform new approaches for diagnosis and treatment of autoimmune diseases.The study was published Feb. 5 in ScienceTranslational Medicine.The human body hosts many different types of bacteria. These bacteria, known collectively as the body's microbiome, play major roles in shaping human health. But sometimes bacteria native to the human microbiome can, under certain conditions, become harmful; these are called pathobionts.E. gallinarum, a pathobiont found in the

First posted on the Shift.ms app

5

@niko91

Last reply

Hello everyone,how long do “bad days” or pseudo-relapses usually last? I’ve been having symptoms for about 3 days now. They are symptoms I’ve had before, and they remain unchanged. In the evenings before sleep and in the mornings they feel better, but they tend to get stronger throughout the day. There don’t seem to be any obvious triggers like heat, etc.

First posted on the Shift.ms app

4

Deleted

@jumpingJacks

When moving your neck triggers sudden electric shocks down your spine

https://youtube.com/shorts/XQSwNK_jwSw?feature=shared

First posted on the Shift.ms app

@RhiaRoo

Last reply

Can an injury trigger foot drop?

Can an injury trigger foot drop if someone has never experienced foot drop before? Background: my toddler fell off the sofa and when I leapt to catch her I twisted my ankle... days later I'm experiencing heaviness in my foot and ankle. Im no stranger to ankle twisting - im in double figures now bu...

First posted on the Shift.ms app

1

@CindyMH

Last reply

Hello everyone 😊. A little about myself. I was diagnosed with MS (after experiencing a few different symptoms (🤔maybe in a period of 3 months or so 🤷🏼‍♀️). This happened November 2008 at the age of 30. After being discharged from the hospital, I went to see a neurologist who started me on daily injections. I don’t recall too much, however I remember the Dr telling me newly diagnosed patients will have a relapse in about 2 years. I was on injections (which injections 🤷🏼‍♀️) less than a year (due to insurance). About 2-3 years later, I again have insurance. I recall hearing anything you take or do to yourself can trigger your “MS”. So because of that, I refused to be back on meds/injections. My way of thinking (maybe not the healthiest) was “It’s been close to 4 years and I haven’t had a relapse or suffered from it. Fast forward ➡️, almost 16 years later I have never experienced anything to do with MS since the time I was diagnosed. I’ve doubted (and still do) of my diagnostic was correct. A few years ago I had some tests done on me and according to Dr- I still show cloudy patches bla bla bla. I’m very thankful and blessed with myself but I’ve also wished and prayed MS didn’t exist. I wish everyone the best, NEVER lose hope or faith and always be thankful you don’t have it worse 🥰.

First posted on the Shift.ms app

6

Looking forsomething specific?

Topics

Looking for
something specific?