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MS trigger

Does anyone believe that severe trauma triggered their MS? I had this just before my symptoms started and sense this could have caused it, no medical evidence obviously but just my view.

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WIDE-Eyed at Night & Worried

Nothing takes me down with MS faster than missing my sleep. I can usually do one night of fewer than eight hours, but two in a row? Last night I was WIDE-eyed and worried. A bout of food poisoning wreaked havoc on my night which I could typically manage, but not two nights in a row. The night before...

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Result of a fall

Good morning. I'm new here and I'm looking for info. I fell several weeks ago and ended up with a minor concussion. Since then I've had nausea in the back of my throat every time I eat or drink. It's the feeling that you're gonna be sick but after a few minutes it goes away. My GP says that the...

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Question, what is everyone doing for pain ? Specifically skin sensitivity, burning feeling. Gabapetin does not help me with anything, it’s triggered by cold temps and I’m just trying to push threw , I’m exhausted and makes working 12 hours very difficult

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Anyone go through this Lhermitte’s sign and Lhermitte’s sign is a brief, electrtric sthock-like sensation shooting down the spine, often triggered by neck flexion

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NIHNational Institutes of HealthTurning Discovery Into HealthMENU< News & EventsMarch 27, 2018Gut microbe drives autoimmunityAt a Glance• Scientists found evidence that a certain gut microbe can trigger autoimmune disease in mice that are prone to such disease and identified the same microbe inpeople with autoimmune diseases.• The results suggest new avenues. At a Glance• Scientists found evidence that a certain gut microbe can trigger autoimmune disease in mice thatare prone to such disease and identified the same microbe inpeople with autoimmune diseases.• The results suggest new avenues for treating debilitating and potentially lethal autoimmune diseases. The lining of the intestine forms a barrier that is crucial to containing gut microbes. If the lining is breached and a gut microbe is able to get into the bloodstream and nearby organs, it can cause disease. Despite the fact that the body has many ways to prevent the breach, microbes sometimes get through.Previous studies have linked certain gut microbes to autoimmune disease, in which the immune system mistakenly attacks the body's own tissues.

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NIHNational Institutes of HealthTurning Discovery Into HealthMENU< News & EventsMarch 27, 2018Gut microbe drives autoimmunityAt a Glance• Scientists found evidence that a certain gut microbe can trigger autoimmune disease in mice that are prone to such disease and identified the same microbe inpeople with autoimmune diseases.• The results suggest new avenues At a Glance• Scientists found evidence that a certain gut microbe can trigger autoimmune disease in mice thatare prone to such disease and identified the same microbe inpeople with autoimmune diseases.• The results suggest new avenues for treating debilitating and potentially lethal autoimmune diseases. The bacterium E. gallinarum (shown in orange) was found in liver tissue.Martin Kriegel lab, YaleThe human gut harbors a complex community of microbes that affect many aspects of our health. Known as the gut microbiota, these bacteria help with metabolism and maintaining a healthy immune system.The lining of the intestine forms a barrier that is crucial to containing gut microbes. If the lining is breached and a gut microbe is able to get into the bloodstream and nearby organs, it can cause disease. Despite the fact that the body has many ways to prevent the breach, microbes sometimes get through.Previous studies have linked certain gut microbes to autoimmune disease, in which the immune system mistakenly attacks the body's own tissues. A team led by Dr. Martin Kriegel at Yale investigated whether microbes breaching the gut barrier were involved in autoimmune disease. Their study was funded in part by NIH's National Institute of Allergy and Infectious Diseases (NIAID), National Institute of Diabetes. and National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS).Results appeared in Science on March 9, 2018.The researchers first tested how mice predisposed to autoimmune disease were affected by antibiotic treatment. In untreated mice, they found bacteria in nearby lymph nodes and the liver at 16 weeks of age, and also in the spleen 2 weeks later. Mice treated with the antibiotics vancomycin or ampicillin had this deadly growth suppressed.Analysis of cultures from nearby lymph nodes, liver, and spleen revealed the presence of a bacterium called Enterococcus gallinarum.When germ-free mice were colonized by E. gallinarum, the bacteria disrupted the gut barrier, moved into the lymph nodes and liver, and triggered an autoimmune response.To test whether depleting E. gallinarum alone could blunt autoimmune responses, the team developed vaccines using heat-killed bacteria.Vaccinating the prone mice against E. gallinarum, but not against two other gu microbes, reduced autoimmune responses6:30 Mspecific treatment can halt autoimmune responses without suppressing the entire immune system, which can have serious side effects.Finally, the researchers examined liver biopsies from people with autoimmune diseases. They found E. gallinarum in liver biopsies from three people with systemic lupus erythematosus, an autoimmune disease that can damage tissues all over the body. Similarly, the scientists foundE. gallinarum in liver biopsies from most people tested who had autoimmune liver disease.Biopsies from healthy liver transplant donors did not have the microbe.Taken together, these findings show that, in those who are prone, E. gallinarum can move through the gut barrier and into other organs to drive autoimmune responses. The resultssuggest new approaches to developing therapies for autoimmune diseases."The vaccine against E. gallinarum was a specific approach, as vaccinations against other bacteria we investigated did not pre mortality and autoimmunity," Kriegel saysapproaches such as vaccination are promising ways to improve the lives of patients with autoimmune disease."- by Harrison Wein, Ph.D.Related Links• Blocking Stomach Acid May PromoteChronic Liver Disease• Changing Gut Bacteria in Crohn's Disease• Infant Gut Microbes Linked to Allergy, Asthma Risk• Food Additives Alter Gut Microbes, Cause Diseases in Mice• Diet Affects Autoinflammatory Disease ViaGut Microbes• Gut Microbes Linked to RheumatoidArthritis• Your Microbes and You: The Good, Bad

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Bacteria in the gut have been implicated in autoimmune diseases, like lupus, that don't primarily affect the gastrointestinal system. But how those bacteria affect the human immune system remains unclear.In a new study, Yale researchers show how a gut bacterium called Enterococcus gallinarum can travel outside of the gastrointestinal system and trigger an autoimmune response. The findings, researchers say, may inform new approaches for diagnosis and treatment of autoimmune diseases.The study was published Feb. 5 in ScienceTranslational Medicine.The human body hosts many different types of bacteria. These bacteria, known collectively as the body's microbiome, play major roles in shaping human health. But sometimes bacteria native to the human microbiome can, under certain conditions, become harmful; these are called pathobionts.E. gallinarum, a pathobiont found in the

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Hello everyone,how long do “bad days” or pseudo-relapses usually last? I’ve been having symptoms for about 3 days now. They are symptoms I’ve had before, and they remain unchanged. In the evenings before sleep and in the mornings they feel better, but they tend to get stronger throughout the day. There don’t seem to be any obvious triggers like heat, etc.

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When moving your neck triggers sudden electric shocks down your spine

https://youtube.com/shorts/XQSwNK_jwSw?feature=shared

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