Hi, everyone. I went into a Holland & Barrett health food shop the other day and asked a lady if they sell Vitamin B12 tablets. I told her I have MS and been advised to take B12 by my MS nurses, and that I have been taking 10 micrograms (µg) as I haven’t been advised on any particular dose. My nurses have seen my containers and haven’t said the dose I am taking was too low, though. I just know that 10 micrograms covers the daily recommended allowance for people, and any surplus would get flushed out in our urine. The store assistant told me I should be taking a much higher dose and showed me their high-strength, slow-release B12 which is 1000 micrograms (µg). This seemed a crazy high dose to me, and I was looking at the lower ones which are still loads higher than what I have been taking, but she insisted a slow release 1000 micrograms would be safe and ideal for me. (It’s also very expensive, though!) Is this level safe or necessary? Are people with MS unable to absorb this vitamin as well as other people can, and higher doses are therefore better for us? Has the 10 µg that I have been taking for the last few years been too low? Could my fatigue and energy levels be improved if I took a higher dose of this vitamin? Should I take these 1000 µg back and get a smaller dose or refund? I’m also wondering if there is anyone here who used to take 10 µg like me but saw a marked improvement after increasing it (and at what dosage).