I’ve been on Tysabri for the last year and found out I was highly JC virus positive in January. I’ve been advised to switch to another high efficacy DMT in the next year. The top choices I’ve been recommended are Lemtrada and Cladribine. I’d like to know from anyone who has had to make a similar choice or who has been or is currently on either Lemtrada or Cladribine. What has been your experience with either DMT? I’m trying to do as much research as I can to help me decide which one to take. I’m classed as highly active RRMS. I’ve previously been on Ocrevus (which led me to develop pneumonia, hence now being on Tysabri), and Copaxone while I was pregnant. My MS is stable and I don’t generally have many day-to-day symptoms, so I don’t really want to start a DMT that could lead to me potentially developing other nasty illnesses or health issues.