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Charity Number: 1117194 (England and Wales)

Registered Company: 06000961

Registered address:
Shift.ms, Platform, New Station Street, LS1 4JB, United Kingdom

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Shift.ms, Somerset House, Strand, West Goods Entrance, London WC2R 1LA, United Kingdom

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@Brite79 

EditedLast reply

Brite79

Hey can anyone put me in the right direction? I’m from Virginia and I’m about to get evicted from my home and I need some help finding a place to live. I am a truck driver and work has slowed down because of the weather but it’s starting to pick back up. But my landlord doesn’t have a heart I guess. I’m in the Richmond or surrounding counties so if anyone could help I’d greatly appreciate it.

First posted on the Shift.ms app
1

@susanmary 

Last reply

susanmary

Heart rate and blood pressure issues?

Hello - I’ve been having a lot of autonomic issues since I had my ms relapse in December - periods of really high heart rate (ranges from 100-160) and very high blood pressure. It’s landed me in hospital a couple of times as the episodes were lasting for hours, landing in resus for 6+hrs with a hear...
First posted on the Shift.ms app
3

@Burkshire88 

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Burkshire88

Does anyone have trouble with Shortness of breath and/or fast heart rate

First posted on the Shift.ms app
6

@Bart73 

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Bart73

Hi! Hope everyone is well. April 8th, 2025 I was diagnosed with Afib. My last heart check up had been 2 or 3 years prior with no mention of Afib. In January of 2024 I was diagnosed with PPMS and had my first infusion of Ocrevus. My question to any of you on Ocrevus infusions is have any of you also developed Afib?

First posted on the Shift.ms app
2
Deleted

@Tia 

Last reply

Tia

Saw this and wanted to share : A microscopic discovery may quietly change how multiple sclerosis drugs are designed and why their side effects happen at all.For years, doctors have relied on immune-modulating drugs to slow multiple sclerosis (MS), even though many come with troubling side effects affecting the heart, lungs, or nervous system. Now, scientists from Weill Cornell Medicine and Memorial Sloan Kettering Cancer Center have uncovered why some of those side effects occur and how future drugs could avoid them.Using ultra-high-resolution cryo-electron microscopy, researchers mapped the exact molecular structure of siponimod, a next-generation MS drug, as it binds to its immune target: the S1P1 receptor. This receptor acts like a gatekeeper, controlling whether aggressive immune cells escape lymph nodes and attack nerve insulation in the brain and spinal cord.The breakthrough? Scientists discovered precisely which parts of the drug help it hit the right receptor and which subtle features cause it to accidentally bind to similar receptors linked to abnormal heart rhythms and other side effects. With this structural “blueprint,” future MS drugs could be engineered to lock onto the correct target more tightly while avoiding the rest.Even more intriguing, the study reveals how nearly identical natural lipids can behave completely differently inside the body, shaping immune, brain, and lung function. That insight may ripple beyond MS, influencing treatments for lupus, psoriasis, inflammatory bowel disease and even lung disease.If medicines could be redesigned at the molecular level to spare the rest of the body, would you accept stronger immune control with fewer side effects?

First posted on the Shift.ms app
5

@HonyBunch 

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HonyBunch

From the heart post

So I'm a very positive individual but every since I got diagnosed in 2017 not so much Im thinking that others feel the same way I do or maybe not maybe its just me When I was getting my infusion one day I was talking with the nurse I said something to her like when you are furthur along in your...
12
Deleted

@Tia 

Tia

So yesterday I had a panic attack I thought it was my heart so the doctor did an ECG it came out good .. he said panic attack and put me on Xanax

First posted on the Shift.ms app

@JordanMac91 

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JordanMac91

MS and Heart Palpitations

Does anyone else here experience heart palpitations/ flutters along with pinches and tingles along the chest / ribs area? I’ve recently been diagnosed and, while I’ve had every cardio examination under the sun over the years, I’m wondering if these sensations are a part of living with MS ? I also su...
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11

@Djcox 

Last reply

Djcox

Does anyone experience heart arrhythmia/flutters with ms fatigue? Breathlessness when walking up stairs etc. I do have a heart condition and AS too but cardiologists can't detect afib it's strange.

First posted on the Shift.ms app
10

@Ralee 

Last reply

Ralee

Heart issues because of MS?

Whats up gang, I hope you're all good. So long story short I suffered a bout of Atrial Fibrillation (AF) for 25hrs with a heart beat between 177-200+ around 8 weeks ago. And I still get (daily) rather unsettling heart flutters, i'm still waiting on a review with a Cardiologist but the tests they c...
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