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Charity Number: 1117194 (England and Wales)

Registered Company: 06000961

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Shift.ms, Platform, New Station Street, LS1 4JB, United Kingdom

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Shift.ms, Somerset House, Strand, West Goods Entrance, London WC2R 1LA, United Kingdom

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Unpublished

@Michellejohn35 

2 Jun 2025 18:17

Michellejohn35

ecently had my MRI results and (as I kinda suspected after a rough few months) had new lesions.I'm currently on Plegridy (moved from Tecfidera as I'm JCV positive and my lymphocytes lowered a lot). Tecfidera worked ok for me, but Plegridy obviously hasn't been as effective. Due to the hard few months I've really isolated myself from people (some I'm unsure even how to reach out to again now) and live alone alone some of the time when my four children are at their mum's. Positive news is, they've mentioned Ocrevus and Kesimpta, which are obviously higher efficacy treatments. Could I ask for any advice people have around these DMTs, please? If you've seen me ask on Facebook or Instagram, then feel free to ignore and not repeat yourself.

First posted on the Shift.ms app

@MK24 

2 Jun 2025 17:22Last reply 3 Jun 2025 11:51

MK24

Ocrevus or Kesimpta

I recently had my MRI results and (as I kinda suspected after a rough few months) had new lesions. I'm currently on Plegridy (moved from Tecfidera as I'm JCV positive and my lymphocytes lowered a lot). Tecfidera worked ok for me, but Plegridy obviously hasn't been as effective. Due to the hard fe...
, United Kingdom
First posted on the Shift.ms app
13

@Julnarlia 

2 Jun 2025 10:17Last reply 2 Jun 2025 18:27

Julnarlia

Kesimpta users

Hello, Im stugulling to inject myself, Im not scared until i have to push the needle inside of me and then i freeze i sit for 30minutes sometimes even longer until i inject myself. Its not that im afraid its more like my body freezes and won't let me do it. Any advice?
First posted on the Shift.ms app
5

@taelove 

1 Jun 2025 18:42Last reply 3 Jun 2025 01:19

taelove

Kesimpta

So I went to the doctor my lession on my brain hasn't progressed so that's good but, I was concerned because I asked my doctor why haven't I been sick yet, my main worry was how often I would get sick due to it supposedly suppressing my immune system but, I have not maybe due to my other autoimmune ...
First posted on the Shift.ms app
6

@elliemb 

1 Jun 2025 14:39Last reply 1 Jun 2025 15:17

elliemb

Hello! Got my diagnosis last month for RRMS and I'm deciding on treatment options at the minute. I'm very prone to cold sores and UTI's and I've been suggested Kesimpta or mavenclad. I know they both have increased risk of oral herpes and uti's so confused as to which to go for. Any advice would be appreciated. Thank you :)

First posted on the Shift.ms app
2

@Bethb 

1 Jun 2025 14:25

Bethb

Mounjaro

Hi, I’m due to start kesimpta, I am also struggling with BMI due to depo to calm ms symptoms down from periods etc. just wanted to see if anyone else has this issue and if taking both has caused any worsening symptoms x
First posted on the Shift.ms app

@sani75 

1 Jun 2025 08:52Last reply 1 Jun 2025 15:20

sani75

Kesimpta vs Ocrevus

Hi I'm new to this chat. I now been approved for either kesimpta or Ocrevus treatment. Could I get some advice or experience on these, please.
First posted on the Shift.ms app
5

@racoonicus 

30 May 2025 21:21Last reply 1 Jun 2025 11:04

racoonicus

Joint pain when taking Kesimpta

Hi. Anyone had joint pain on kesimpta? Took first dose yesterday and wrist became really painful after a couple of hours then got back ache and now I have pain in hip. Thought I had just sprained wrist, although I don’t remember doing anything, but now the other areas are painful, I’m wondering i...
First posted on the Shift.ms app
2

@Hanmags 

30 May 2025 09:25Last reply 30 May 2025 12:16

Hanmags

Moving to Ocrevus

I’m moving to ocrevus from Kesimpta and I’m a little nervous! I’m moving because I don’t really have any symptoms thankfully but I get incredibly tired for about 24 hrs and it really bums me out once a month. I also am thinking of having children in the near future so it seems like the logical switc...
First posted on the Shift.ms app
17

@racoonicus 

29 May 2025 19:28Last reply 1 Jun 2025 11:07

racoonicus

Kesimpta. First dose

Hi. Had my first kesimpta injection this morning. Pls tell me it gets better. By 4pm I was starting to feel bad. Aches, pains, headache, freezing, skin hurts, joint pain. Does anyone know how long it lasts for. I’m hoping I’ll feel better in the morning. Good this is awful. If it’s like this every t...
First posted on the Shift.ms app
10
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