@alephbet

Last reply

alephbet

Ocrevus vs Tysabri

Good morning, everyone, I spoke with my MS nurse about possibly switching from Tysabri to Ocrevus later this year. My neurologist isn't inclined for me to switch since "Tysabri is working so well for you." Meanwhile, I just read this morning that the neurology director at my hospital, Dr. Anthony Reder, worked with Genentech in developing ocrelizumab (Ocrevus). He was involved in the first clinical trial here in Chicago. He considers it a breakthrough: "this drug is at the highest level of benefit of any drug we have, and it also has the fewest side effects." Anyway, my MS nurse told me that me that Tysabri works by strengthening the blood-brain barrier against T cells. But she wouldn't tell me if Ocrevus works the same way (my neurologist will tell me at my next appointment in January). Hypothetically, what if I switched to Ocrevus, but it wasn't as effective at slowing down the progression as Tysabri once was for me? Thank you for your help and your patience. Alephbet