dimethyl fumarate
Hello,
I’ve taken some time off this platform. I was so positive and ‘strong’ when I was first diagnosed last year but it’s been a bit of a rough ride emotionally since - I’ve just stuck my head in the sand and pretended it’s not happening to me. This was actually super easy for me as I’m lucky to only have had mild symptoms to date (fizzy legs, v mild ms hug). Anyway, I was going to start kesimpta last year (v soon after diagnosis - again, I was v luckily diagnosed within months of my first symptoms) but got cold feet. Would I be ok injecting myself every month? Is the dosage too high? What are the long term impacts of depleting b cells at such a large rate etc etc…all questions I should have asked my neurologist at the time but realise now I was still in shock. I also suffer from psoriasis and having flare ups - I read b cell depleting therapies can make psoriasis a lot worse. I messaged my ms nursing team about some of my concerns and why I wouldn’t be going forward with the treatment. They’ve since emailed me to suggest dimethyl fumarate as it’s a treatment used for both psoriasis and ms. It’s less effective but still ok in lessening relapses and slowing potential disabilities. Question is does anyone have experience taking this drug both short and long term? As my symptoms are, thankfully, quite mild atm, is it a good one to start with?
Thanks! (Soz for the huge back story 😂)
Hello @Kfis I have taken both treatment options and for me Kesimpta fits in well with my lifestyle the better of the two drugs. I have been diagnosed with MS now for about 12 years and since starting Kesimpta 18 months, I almost feel free of MS. I wish that Kesimpta was available for me years ago before the Tecfidera became available, but it was "then" the DMT to get on. I suffered from some side effects on the Tecfidera and after years on the drug, it simply wasn't working for me anymore. The Kesimpta on the other hand is brilliant (IMO) one injection per month, no side effects, no anxiety about remembering to take a table twice a day with food, etc. The injection is simple and doesn't hurt too. Good luck whatever your decision.
Yes I took techfidera expecting loads of side effects but didn’t have any sides effects. I continued to have relapses though so was swapped to fingolimod and now spms and taking siponimod. I prefer to take tablets rather than injections/ infusions xx