So, when I was first diagnosed, I was given Avonex. A year later, after I was tired of (needle every week) stabbing myself. It wasn't bad but every spot, the side effect, hurt as my skin was being eroded. Now, I'm starting mavenclad. I have to prep for shingles, etc. But no more needles. I have tattoos. But the individual needles can go away. Giving myself needles is not a bad thing. Ex diabetic wife, I helped.