WTF is going on? Stay in, don't stay in but work from home unless you can't and therefore, with 12h notice, get off your arse and cycle to the building site. And so on and so forth. - The long-term sick, disabled, vulnerable? Hmmm, cripes, tricky one, gosh, hadn't really thought of those johnnies. Where do they live? Anyhow, the entire set of communications (the letters and texts) has been so spectacularly mangled I can only imagine that Boris (Trump with the thesaurus upgrade) has been advised to steer clear of mentioning anything that might really get him onto a sticky wicket. Knock the topic into the long grass and just hope it stays there. *sigh* - Have you noticed that the alert-o-meter graphic seems to have been lifted straight from the Nandos heat level meter? I have never been to a Nandos (am old, am also a food snob as I used to have a firm selling organic food. Nandos uses the lowest quality chicken imaginable...) but it did pop up v quickly on Twitter. See for yourself: https://business.facebook.com/NandosCanada/photos/a.10150143528640313/10161605389815313/?type=3 - I want any leader to succeed, even by the most basic of measures, yet we seem to have managed to get the fellow that was always picked last for teams to be in charge, along with his similarly useless pals. I really am beginning to despair that we'll manage to get lower in the tables. In this instance, lower or even last is the best outcome. This seems to have escaped the Ginger Bone-Spurs and the Bumbling Buffoon. They both seem to think that the top of the table is a good thing. - I am not a natural-born worrier. However, I am becoming moderately concerned about Ocrelizumab as it pertains to immunisation. If you get this - because I don't - then please share your understanding. I can't seem to get an adequate reply as it pertains to natural immunity. As I understand things: - 1 - Being on ocrelizumab does not confer any additional risk if and when I catch Covid-19. - 2 - Ocrelizumab selectively depletes B-cells but the T-cells are where it is at regards fighting an infection. BUT it does seem to blunt vaccine response. In plain English: the vaccine(s) as will certainly be developed and deployed in the next 18-24 months are unlikely to work in ocrelizumab recipients. - 3 - I fully expect to catch Covid-19 at some point. I think it is unrealistic to think otherwise. As a result, I am trying to be in the best shape possible regards minimising its often brutal effects. - 4 - Here's the rub. If I catch it, recover, and in normal circumstances will have generated immunity to it does the ocrelizumab washing around in me mean that I won't develop immunity and therefore will be as susceptible to catching it again and again? That would be very dull and I am guessing that repeated boughts will wear one down pretty sharpish. - Thoughts? I know a lot of folks read this blog, many of whom are far far cleverer than me. These are utterly non-science based musings. I post it here because the next stop is www.MS-Selfie.com . Thank you .