Last reply 8 years ago

I’m taking my injections since the middle of October everything is fine it’s just the side effects from the it when I take it I go to bed but within an hour I’m freezing cold my head is thumping and when I wake up the next morning feel like iv the flu. Don’t no how long it lasts?

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8 years ago

Hi Leanne-I know it doesn’t help much but everyone really is different. My flu like symptoms after injecting stopped after not that long of taking rebif. On the other hand, the morning after I inject even now (going on 9 months later) I have an excruciating headache until almost midday which painkillers don’t touch. I guess it really is a case of just seeing how you go and keeping your MS nurse informed.xx

8 years ago

Hey there …. I’ve been on Rebif with the Rebismart auto injector now for over a year. That’s no good that symptoms are doing that to you.

Fortunately I didn’t have any symptoms from it like yours but they are supposed to go away after a couple of months. Just stick it out for a bit longer and see how you go.

Otherwise I’d say you’d best report it to your doctor as some people can be allergic.

Hope that helps … All the best 🙂

8 years ago


My partner’s been taking Rebif for 15 months now. She had really tough side effects just like yours for the first 3 or 4 months before they started to gradually reduce. It was 6 months before she was free of side effects. She used to manage them by taking paracetomol before her injection and maybe ibuprofen in the night which reduced the sweating a bit.

She’s been relapse free since starting though and now does injections at 7PM with no noticible side effects at all.

8 years ago

My side effects lasted for about 6 months. But I have since discovered that I have NABs (neutralising antibodies) so that’s probably why the flu-like symptoms disappeared – because it wasn’t actually working properly! I’ve been on Rebif for just over 3 years and only recently got tested for NABs. In the process of switching to Copaxone now.

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