@monks 

Last reply

monks

Plegridy Vs capaxone

Hi, I've been on plegridy for about 8 months and have found it a struggle, I feel like death on injection weekends and due to a busy work / life / family / in-laws commitment not a great deal better on the rest. Have talked to my consultant and on review after new mri's, the treatment has stopped what was previously active MS, but we are both concerned about how lousy I feel. The upshot is the only alternative that he is offering is capaxone. I'm not keen on idea as although I'm finding it hard, plegridy seems to be working. Does anybody have experience of both treatments who could share how it was for them. Oh and Merry Xmas x
@BeatnikSpirit

Hi, I've been offered the choice of the two. I've no experience with either. I'm planning to go with Copaxone from Feb. I'll let you know how I get on. Merry xmas.

@ItsMewithMS

I was on Copaxone for 11 years and it seemed to hold me for awhile and back then (2005) it was one of two options. I basically stayed on it too long...it ended up being a "one and done" type of therapy. I should have been switched up as lesions continued to mount and there were occasional relapses. Instead I was only switched to Rebif when I switched Neuros. I was on that a few years with no activity but likely because I had transitioned to SPMS. I'd encourage you to research them both and even other options that may be the most effective for you. Many Neuros are still following the "escalation" model and only reacting to symptoms and a very delayed reaction so they are always chasing after your symptoms. Current theory would better support getting in front of MS and treating it MS more aggressively which is why Ocrevus is the new most widely prescribed DMT using the "induction" style. Matching your "style" with your Neuro's is important. How much risk you are willing to take, how active your MS is, etc. MS Treatment options and styles: https://www.youtube.com/watch?v=51B1VpGchDc When is Copaxone still appropriate? there are a lot of newer/stronger DMTs out there:https://www.youtube.com/watch?v=Sd69KmEpsWM At about 30 minutes in Dr Boster starts to talk about all the DMTs out there in a funny physical demonstrated way https://www.youtube.com/watch?v=7gHhdwKK5uc I can't see that he directly reviewed Plegridy but you could search more on you tube for it. I do see he listed as a low efficiacy DMT. That may be the right approach for you and it may be very safe in exchange for that. This group may also have good information as you thought it might. If you put it in the little magnifying glass in the upper left there are several hits and some discussions in the past just like what you are asking now- may be a good place to check and some members to check in with- I see a lot of injection/DMT reactions to Plegridy as well. Good luck!