There’s loads of info on here already if you use the search function. They’re very similar drugs - both b cell depleters. So their side effects, risks and efficacy are pretty much the same. Personally, I chose Ocrevus because it’s a six monthly infusion so I don’t have to think about treatment the rest of the time. Also it gives me more contact with MS services - otherwise I’d never see or hear from an MS nurse 🤣 I feel like intravenous is a more reliable route than subcutaneous and the higher dose of Ocrevus is likely to be more effective especially as I have a higher BMI. But this is a personal opinion and not fact! Some people prefer kesimpta because it means they don’t have to travel to hospital, and can ‘top up’ monthly - as some feel there is a ‘wearing off’ effect from Ocrevus (the ‘crap gap’). That doesn’t really make sense as your lymphocytes stay low for as long as a year after Ocrevus but it seems to be a common enough phenomenon that there is maybe something to it. Basically there’s not much to choose between them. Whatever suits your lifestyle best!

@mellowmedusa thank you so much for taking the time to reply. I think I'm leaning towards the Ocrevus for the reason you say - only having to think about it a couple of times a year. I suppose I'm just concerned about swapping one kind of feeling unwell for another if I'm going to be catching everything going illness wise!