@pinkie100 

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pinkie100

Tysabri - few symptoms but new lesions

I was diagnosed in June 2019 having woken up with pins and needles in my hands in January. No previous symptoms. Pins and needles extended to whole body from chest down and I experienced MS hug a few times. After a couple of months things seemed more or less back to normal and although the pins and needles feeling in lower arms and hands persists it's an inconvenience rather than painful. Scans in March showed two new lesions although I'm unaware of new symptoms and I feel fine. About to start on Tysabri (thankfully JCV negative at present) but feeling concerned as physically I feel fine. Has anyone had a similar experience and gone on to have treatment, especially Tysabri? Thanks for listening.
@ItsMewithMS

I was Dx in 2005 when there were only a couple of DMTs available. I was put on Copaxone. Now it is considered a low efficacy treatment. While on it I had a few attacks over the years that were quickly staunched with steroids. I had active lesions at those times but was surprised how many lesions had formed with no apparent symptoms. Although I was in my 30's I must have had great neurological reserve as my brain could quickly rewire around the damage. I think the lesions in my spine were more impactful and the source of my foot drop, gait issues and balance issues. I think the video on progression lays out how MS works in a way I can understand and visualize: https://www.youtube.com/watch?v=fZPQ48N-nIs&t=68s It is obvious that stopping any lesions is very important and I did not realize how important at the time they were forming. I remember thinking, "ok, a few more lesions but I feel fine"...they come back to bite you later. As my neurological reserve drops as I age I am now feeling them. This clip talks about MRI activity and treatment https://www.youtube.com/watch?v=F9-_AgSEmT0&t=1s He has several on reading MRIs and the one that associates the location of a lesion with it's likely impact I thought was great-

@pinkie100

@itsmewithms thank you for replying. I found the video very helpful and informative. Everything is a little overwhelming just now! Thanks for taking the time to help.