A fun story from the hospital, I went there to do some blood work and witnessed a conversation of a guy with a neurologist and later talked to him. So, the guy was diagnosed with MS for 7 years, taking Tecfidera. It turned out, that he had a condition that prevented him from absorbing some vitamins (I don't remember the name, persistent anemia, or something like that). Despite no spine lesions, stable head MRI with couple of small inactive lesions, no bands in the CSF he was comfortably diagnosed with MS by the neurologist. The guy was both relieved and extremely angry, which is understandable, but it prompted me to think of misdiagnosis of MS, how common it is? Why does it happen? Im not talking about myself, my case seems to be clear cut (based on MRI changes and LP), but -- in general -- I thought that the neuros diagnose you with MS only when they are certain that this is a correct diagnosis (it happened in my case, at least, and most of the people I've talked with). Any comments?