If you're unsure, check with your GP, esp if you're on other meds too. Every case is different. I was on Citalopram for 8yrs ish. GP said take it about 2hrs before bed (not *at* bedtime), which worked fine for me. He also said that if that didn't work, to try it in the morning instead - so I reckon the evening is more usual to begin with, but trial and error is allowed if evenings don't work. But I would check with GP before changing anything major, just in case...