honestly, not much of a difference . i definitely made sure to have the recommended aspirin around the first few days but now i don't even bother with that. i think i had a full week run up to starting the full dose though. i am aware i had bad cramps once or twice but that was happening it was the half dose or full dose. 

I hope it goes ok for you! just try not to worry too much about what you're doing, look after yourself and try not to get stressed out! 

Thanks guys! I am such a worrier but I have told my work mates not to panic if I turn bright red again. It only happened on the first day so here's hoping and I'll have aspirin at the ready this time:) thanks again xx

I didn't have any problems transitioning.  Haven't really had any problems at all with it (occasionally flushing of skin but that's about it)

I am on day 4 and my pain has come back with avengence! Other than that I have not really noticed anything else x

Hi Lauralou, nope no real difference :) i hope it goes OK for you, let us know how you get on!

Hi lauralou

I didn't have any side affects and didn't notice any change in transition.  I was on techfidera for 10 months and got on really well with it.    I had to come off it due to a low lymphocyte count.  I'm gutted as I was getting on so well with it.

Hope it goes well for you 

good luck

x

Hi lauralou,

I had the sore stomach, beet root colour flushes!! and itchy skin with the first dose but it went away and nothing like it any more even after starting the full dose. It'd be much less or even no side efeects, If you take it after your meals or even better when taken with a slice of toast and peanut butter!

Good luck

Hi @Sarah_T how low was your white blood count? I am due to start Tecfidera next week and my white blood count is slightly below normal. 


@Phillip, mine was 0.25 when I stopped taking it.  I think normal is between 1 and 3. And they only start monitoring monthly when you fall below 0.5.  Good luck. I think its an excellent treatment & wish I could have stayed on it.

I'm sorry to hear that. I think normal is 3.5 or something like that and mine is 3.0. I am getting my bloods done every month because of this. Do you know if yours were normal before starting?


Hi everyone, 

These posts have really helped me. Currently trying to decide whether to switch from Copaxone to Tecfidera and I'm really stuck on what to do. Has anyone heard anything about whether it affects your fertility or not? And how are the sickness side effects? Any honest accounts would be brilliant as I really don't know what the best thing is to do :(

As regards fertility, there's this report from New Zealand that has a section on it (Page9) :- http://www.medsafe.govt.nz/Profs/Datasheet/t/tecfideracap.pdf

I didn,t notice much change. Just the usual flushing, nausea etc. but it has all gone now.  Can i ask if anyone else on this drug suffers from a constant runny nose? I have told my consultant and she is bringing up at a meeting next week

Yes I do too! It's very annoying and comes on all of a sudden when there are no tissues at reach! Must remember to keep some in my bag! X

@ksmiffy I did used to get the runny nose quite alot. If I bent down to pick something up I would get a drip fall from my nose randomly. It was pretty annoying and I had to make sure that I had a tissue to hand.

Its doesn't happen that so often nowadays and i've just completed 10 months of taking Tec. I have had a constant cold for the last 6 weeks so maybe haven't noticed the drip so much

Hi... I have just been prescribed Tecfidera ... Has anyone that's taken it had any evidence that it's worked / working ?? I'm told it's a new drug and I'm a bit nervous about taking it.. I can't find much info on how it actually
Works ... Thank you xxx

Hi, @laura-louise-1982 . There's been a lot of discussion on the forum about Tecfidera. Yiu can find the rest of them by using the forum search function (Manifying glass towards the top left of every page)

But, here's some details:-

https://www.mssociety.org.uk/what-is-ms/treatments-and-therapies/licensed-disease-modifying-drugs/Tecfidera
https://www.mstrust.org.uk/a-z/tecfidera

And a bit of background, which shows that Dimethyl Fumarate was being used for other conditions, before it became an MS DMT:-

https://en.wikipedia.org/wiki/Dimethyl_fumarate

Hi. I'm due to start the full dose of tecfidera tomorrow after being on half for a week. Anyone experience a huge difference in the transition?  Thanks in advance xx