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Herpes Outbreak after Lemtrada

I am waiting to be scheduled for Lemtrada Round 1 and am hopeful and apprehensive at the same time. I had the recommended Shingles vaccine and will be prescribed Acyclovir when I begin the infusion process. The fact that they recommend dual preventative measures makes me think an outbreak after Lemtrada would be a real doozie. Does anyone have experience with this? Thanks

@fishnets Apologies for not replying sooner - I'm blaming the busted arm for not being online recently. Acyclovir is a standard 28 days treatment in the UK post lemtrada for everyone (in the US they keep people on it for a lot longer) It is used to help prevent recurrences of the herpes virus (coldsaws and the like) post treatment. Shingles innoculation is something again that commonly happens in the US (you can only get this done privately in the UK) Shingles is a reactivation of the chicken pox virus which continues to live on in the spinal fluid can at times of extreme stress or low immunity can reappear as shingles post lemtrada. I had my 28 days of acyclovir post round 1 and 2 but never had the shingles vaccination - I won't even have a flu vaccination these days post treatment.


Hi fishnets. I'm guessing you didn't have chickenpox as a kid then if you've just been given the shingles (herpes zoster) vaccine? I didn't need the jab but I do always have the Acyclovir tablets to hand (repeat prescription) even 4 months post round one as cold sores (herpes simplex) are often attempting a comeback! Herpes is very opportunistic on a weakened immune system but is no big deal as long as you're alert to it and act quickly. But shingles can be most unpleasant. If you've never been much of herpes sufferer then, like Tracey D says, don't worry about it but take the recommended 28 day course. If you do get recurrent cold sores or sacral herpes (most people get one or the other) then ask for a repeat prescription of tablets and just keep them in the cupboard. Lx