Sorry i've no advice I can give you. I've not even been assigned any dmd treatments as yet. I'm not even sure which ones going to be my best option although initially my neuro mentioned interferon.

I can only offer my experience on Betaferon, which may be similar.
The first injection resulted in flu-like symptoms, which gave me a pseudo-exacerbation, so I got to bed. Had the shivers, had the sweats. But I was OK the next morning.
I took the second shot a bit later in the day, with a view to being in bed by the time the flu-like symptoms got me.
These symptoms disappeared after a couple of weeks, but would re-appear in very isolated incidents.
It's all workable.
Hope this helps.

Hello Jouk, i was taking Rebif from December until Early June. A nurse from the supplier came round to show how to inject ( i was using the auto inject machine thingy) which was helpful, do you know if you are going to be advised by a nurse on where and how to inject? The days i chose i would take 2 500mg paracetamol at lunchtime and then injected at 4-5pm (to give most length of time between injecting and work next day) and had another two and then two more before bed. I did have flu like symptoms to begin with but not too bad with sleeping through the worst and this lasted a couple of weeks gradually decreasing over that time.  The nurse said to take ibuprofen as well, but i can't due to a stomach issue.
I would occasionally get a bad day after the injection and usually at the end of the week, also if you drink i found that having a couple of beers made me feel like i had been out all night the next day. 

All the best with it

Take some Ibuprofen, Tylenol, or your preferred fever reducer of choice when you inject. Otherwise, a few hours after injection, it can hit you like a truck. And I agree about the beer comment made by <a href='https://shift.ms/community/people/macready/' rel='nofollow'>@macready</a> above.

Hey,
Ive been on Rebif since 2010 and not had one relapse since! It was hard at first to get use to having inject myself, but eventually i got use to it and it just takes 2 seconds using the Rebiject thing!
I inject in the evening before i go to bed every Monday, wed and Fri and take a couple Paracetemol or ibuprofen so I can sleep off any side effects.
If you dont take any paracetemol you will probably get flu like symptoms, feeling shivery n achey and sometimes if ive run out of paracetemol when i have to inject ill wake up in the morning and my eyes hurt to move around feel achey all over?! bizarre! but that could b different for everyone?!!
Hope this helps and good luck, you'll be grand! :-) xxx

Hey I was on Rebif for just over 12 months and had the Rebiject or RebiSmart ... autoinjector as well.

takes literally no time at all to do. The flu symptoms should wear off after a few months ... should ... The kit you get with it (well here in Australia) has a chart and stuff where to inject just rotate the sites and you'll be fine.

I took mine mon, wed, fri (morning) just so I could get it out of the way and head off to work. I was lucky didn't really have any reactions to it. All the best though!

Fisrt time on treatment,decided to go with rebif, going to be starting treatment in a couple of weeks 
any adive or suggestions????????? when to take,what side affects and how long do they last.

rebif help and advice