I’m curious if anyone had severe fatigue accompany their initial Tysabri injections? I’ve been on Rebif which they took me off because I was having constant fever symptoms associated with the medicine. Then I went on ocrevus and I loved it. Felt like I was somewhat back to normal. However, when my MRI showed two new lesions they took me off of it and put me on Tysabri pending a negative JCV test. Since I started Tysabri, I am nothing but tired. Crazy tired. I know fatigue is a common symptom of MS but I never had it before… in fact, I’ve suffered from insomnia more than anything. I see my neurologist on Monday and I will push for some answers. I already have an MRI scheduled a couple weeks from now. I’m afraid Tysabri gave me PML or something. I refuse to believe this symptom showed up exactly at the same time as switching to Tysabri. Anyways it’s extremely frustrating. I just started a new job and I’m doing really poorly because I can’t remember much and I’m so tired. I don’t have the option to go on disability and I don’t have family to support me. I don’t want to unalive myself but more and more it’s feeling like the only option 😥