Never taken myself but have read about it some before and is positive from what I’ve saw. I partake in the lords lettuce all day every day just had my weed day going to the dispensary to re stock and knowing how well that helps with ma from long before I even had ma as my one dealer from the dark days sold it bc it helped his wife who had ms and was really bad. She couldn’t talk or move herself anymore but he would help her to hit a joint and could see her body calm and from then on actually looked at the amazing aspects of it not the little high school wanna get high mode and from what I’ve read about sativex it’s a good alternative if getting legal weed isn’t an option. I’ve read its good for calming our body’s down and Ik normal weed is great for that so seems like they are doing it right. Can’t give any actual statements on it as I’ve never taken it but the lords lettuce is amazing for us msers