@semaj70 

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semaj70

Switch from REBIF 22 to Ponesimod or Kesimpta

I have been on REBIF for years and my consultant has suggested researching the possibility of switching to Ponesimod or Kesimpta which weren’t available when I first went on my REBIF 22 treatment (approx 20 years ago). Has anyone any similar experience? The REBIF has been successful in my case, steadying out to no major relapses for a long time, but the option of pill format or once a week injections is tempting. I’m currently injecting three times a week and the site areas are uncomfortable, but certainly not unbearable. I have no other noticable side effects. Obviously I’m thinking ‘if it’s not broke then don’t fix’, but the option of switching to something which might restrict relapses and help me longer term (I’m 54) are tempting. Also, I have concerns changing meds unsuccessfully might mean I might not be eligible to go back to Interferon. Any advice or research pointers welcomed.
@RC83

I haven't taken either but if I were in your shoes I would choose Kesimpta because on paper it is a much higher efficacy drug than Ponesimod.

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