“I’ve been on Ocrevus since 2024 after 8 years on Lemtrada — here’s what no one told me…”
Lemtrada felt intense but spaced out. Ocrevus is regular and more draining than I expected — physically and emotionally.
After my last infusion (which didn’t even finish properly), I’ve felt worse. Even my dog knows I’m not right.
I’m now tapering off Zopiclone, using melatonin and calming routines like legs up the wall — small things that help a bit.
📅 I’ve got an appointment with my neurologist tomorrow because, right now, it feels like the side effects of Ocrevus are outweighing the benefits.
Has anyone else been through this?

Hello, my Son Ali was a Lemtrada patient for many years, his MRI was showing brain shrinkage, so Doctors strongly urged us to let Ali take the 2year infusions. But he its on anything right now (Praise The Lord) doing well MRI is the same. Although Ali is bed-bound we keep him active
I only took 3 infusions of Ocrevus since the side effects were terrible for me and had 2 anaphylactic reactions I am switching to Kesimpta. I have not started the Kesimpta inj but I am looking forward to it so I don’t have that reaction ever again.