@Kesimpta and side effects on Shift.ms

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@pepperpot1

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Kesimpta and side effects

Does anyone take Kesimpta and has found that everytime it totally wipes you out for 24-48hrs. Taken 6 doses now and still get exhausted and in pain with cramps from it everytime. I couldn't even open my eyes for with the fatigue immediately after. Also seem to get a crap gap, is this a thing with Kesimpta?

First posted on the Shift.ms app

@Kushman420

Hi. I've been on Kesimpta for over a year and haven't really had any bad symptoms initially I had some fatigue issues someone recommended taking at night so you sleep through it. Haven't experienced crap gap since I've been on it Ocrevus was a different story. Reach out to the Kesimpta nurse and see what they recommend. Hope you get this figured out 💪🧡

5 Jul 2026 18:37

@Lindushka

I haven't had any side effects since the first ever dose, but crap gap is real, at least for me. It comes few days before my jab, enhancing the only symptom I have had. Talk to your nurse, sounds like your case is different than most x

5 Jul 2026 19:24