Looking for a bit of advice from those who’ve been there. After nearly 20 years on Tysabri, my latest JC virus blood test has come back high positive. I’m not going to lie, it knocked me a bit. Tysabri has been such a huge part of my MS journey. It’s worked incredibly well for me and helped me get on with life, so the thought of eventually moving on from it feels strange. I had a quick chat with my neurologist yesterday. There’s no immediate need to switch and nothing is changing right now, but Ocrevus and Kesimpta were both mentioned as possible next steps.i have a meeting with him at start the start of July. Has anyone here moved from Tysabri to either of them? How did you find the switch? Was there anything you weren’t expecting? Anything you’d do differently? I’m off on holiday next week, so I’m trying not to overthink things before I speak to my neurologist again when I’m back. In the meantime, I’d love to hear some experiences. Thanks everyone.