I generally find that the day of my infusion, my sensory symptoms are worse…and probably the day after infusion as well. I have heard nurses tell me that a lot of patients can tell when they are due for infusion—-that they look forward to their infusion because it gives them a boost. Personally, I have never felt a “boost” from my Tysabri. But, I do understand that it is a preventative medication. Maybe ask your doctor is there is something that you could take to counteract the aching from your injection. Perhaps even Ibuprofin or like Benadryl???

Yeah I had the same issue, had my 2nd one 9th September and still struggling with more pain in back/hips/legs and tingly arms 🤷🏻‍♀️ hoping it settles soon xx