@I have had MS for 18 years, and no serious problems and haven't had any changes in my MRI in 14 years. However now I am becoming weaker in my legs and starting to have balance problems. Can symptoms change even with no additional lesions? on Shift.ms

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@Casey2007

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I have had MS for 18 years, and no serious problems and haven't had any changes in my MRI in 14 years. However now I am becoming weaker in my legs and starting to have balance problems. Can symptoms change even with no additional lesions?

First posted on the Shift.ms app

@friendly_james

Hi, paper linked to below covers this clearly. https://journals.sagepub.com/doi/full/10.1177/17562864211066751 MRI evidence is not a complete or even 50% complete indicator of disease progress. We have been led up the garden path, so to speak. We might do well to bear in mind that MRI does not picture all brain matter. Therefore MRI imaging could not be a measure of disease activity.

27 Nov 2024 03:10

@Carrie

Short answer, yes. Best wishes! If you get any medication changes I hope you have a best fit solution soon.

27 Nov 2024 03:34