Has anyone else experienced a lot of depression after a Tysabri infusion? I had my 2nd infusion last Friday, and I’ve been struggling with my depression quite a bit since then. I’m trying to figure out if anyone else has noticed a similar pattern after their infusions. If you take Tysabri, I’d love to hear what your experience has been — especially after your first few infusions. Did the depression happen after your infusion, and if so, how long did it last?