@Murray 

Last reply

Murray

monoclonal antibodies

I may have to take a drug based on these. Have you taken them and have you any advice?
@bethyannelies

Which one? I had lemtrada. Pre lemtrada I was relapsing every 2-3 months, my last relapse was disabling and caused complete paralysis from my waist down... For me it has been very successful, I haven't relapsed since (2 years since round 1) and I can now walk and only use my wheelchair to go out for the day, like shopping, zoo, anything with a lot of walking. It is an aggressive treatment so not to be taken lightly, but the benefits definitely outweighed the risks for me. As for follow ups, I can't confirm if I have any new activity yet but am due for my MRI anytime now. Hope this helps, if you want to know anything more specific just ask :)

@DominicS

Murray, there are many. The mab at the end of the drug name is the identifier. Some are animal, some are humanised (ocrelizumab from mouse pancreatic cells) and some are human-derived. This is a meta view: https://en.wikipedia.org/wiki/Monoclonal_antibody Ocrelizumab Natalizumab Alemtuzumab Rituximab Ofatumumab (on the way) Are the ones that come to mind for MS. I am on ocrelizumab (Ocrevus) and am due to have my fourth infusion in June/July this year. It has been remarkable in so far as I don't feel a thing. Nothing. My MRI is not active though. They are relatively new drugs and are well monitored. Not like taking ibuprofen but highly unlikely to harm you as the monitoring is so v good. Use the search function here, type in ocrelizumab and see all the posts.