I've just read this via the Tysabri website on facebook. I'd only been saying to Ghada a couple of weeks ago that it'd be interesting to know how Shift.MS came about. There should be a little section so that people know - I did find out bits and pieces before now. This site has been the only place where I've really got any information. It's great. (Mind I am finding it difficult to navigate the new system but I'm sure I'll eventually get used to it) Well done George!