Vixen and Kateb it is so good to hear of two MS’s that have the same thing going on as me. To be honest I have felt completely alone with my daily struggles of this changing direction in different parts of my body. Remission just does not figure in my existence and my neuro is accepting of this hence the Ocrelizumab to try and cover the primary progressive angle if it is that. I can’t thank you enough for your replies. They have helped enormously so thank you. And stumbler your advice is always welcome.