Marlo: Is oral chemotherapy an option for people with MS?
Professor David Baker, Researcher: Oh, Lemtrada by another name is called Alemtuzumab, yeah? And Alemtuzumab, if you take it apart, so ‘mab’ means it’s a monoclonal antibody, ‘alem’ is just the name they’ve made up, ‘tu’ means it was originally made to treat cancer. So Alemtuzumab’s a chemotherapy agent, but it’s used to treat multiple sclerosis because we believe that MS is driven by the effect of the T cells and you can get T and B cell cancers, and that’s where alemtuzumab’s used. So that’s one. Cladribine, essentially is another one. Mitoxantrone, another one. So there’s a lot of chemotherapy drugs that have actually been used in MS and they work because they kill active cells and the active cells are the white blood cells. So, yeah.
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