I’ve done around 4-6 hours reading almost everyday regarding Ms and how to slow progression etc as I’m terrified with all the issues I have had.
I’ve come to the conclusion that glutamate is key or the removal of it is, and I’m not the only one.
It’s been implicated in me, Alzheimer’s, ocd, als the lot!
All the healthy eating programs for Ms contain foods that lower glutamate and increase gaba and glutathione the good guys.
The Ms smart trial is using riluzole and fluoxetine, both have lowering effects on glutamate. Even biotin activates the Krebs cycle implicated in glutamate lowering.
The supplements suggested, l theanine, NAC, nag, inositol etc they all have the pro glutathion GABA and anti glutamate actions.
Now don’t get me wrong this isn’t proven at any level really other than mouse models and some loose phase 2 trials of numerous drugs but I’m convinced this is one of the keys. Even mindfulness reduces glutamate by promoting GABA!
I mentioned this to the chaps at Barts who
Have mentioned that they have an interest in it and are awaiting funding for some trial which they are keeping tight lipped about.
This i don’t believe is so implicated in the inflammation stage but I believe it’s huge in the progressive stage. The messential vitamin contains a lot of compounds that impact glutamine levels, so surely it’s worth a try?
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