Last reply 9 months ago
Cladribine

HI All,

I’ve been having a lot of relapse these past few months while being on Teqfidera but been told to no longer take this drug as I’m being offered 2nd line treatment.

Has anyone started the drug Cladribine ? thinking of starting this.

I’ve done some research but was wondering if anyone has experience with this drug? I know it’s new so I’m not expecting a lot.

Luke.

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stumbler
10 months ago

@lukerussell31 , Cladribine isn’t a new drug. It’s only recently been used, with some success, to treat MS. For this purpose, it has been rebranded as Mavenclad.

So, unlike most new MS treatments, this drug has an extensive track record.


sciencegeek
10 months ago

Hi. I’m about to start taking cladribine, unless there’s any unexpected chnage of plan. While I can’t give you personal experience, I could let you know how I came to my choice to stop tecfidera and start cladribine. I can also private message you (if you send a friend request) the email address of the neuro at the Royal London who is seeing me. His team have been amazing at answering my questions.

The key trial to read about is the CLARITY trial. There is acually a lot of data about long-term effectiveness as the first trials for MS were over 10 years ago, and it has been used off label for a few years in the UK already.


mikemanc
10 months ago

I’ve been asked by my Neuro to come in and decide where I should move to next after getting low liver function results whilst on Gilenya. Claribine or Tecfidera have been suggested with me leaning more towards Cladribine. I’d be interested to hear if anyone on here has been taking it and how it’s working out for them too.


emmad1988
10 months ago

Hi Luke. I started Cladribine last August/September so am due to have my second dosage later on this year.
So far so good though. Have not had any new episodes and my latest MRI in December did not show any new disease activity. The injections itself are relatively pain free and I had no injection site soreness, just a little lump under the skin which went after a few hours. I have been lucky that i have not suffered with any illness other then a winter cold. So for me it’s been relatively plain sailing. The only downside is the 3 monthly blood checks….not ideal when you have a terrible fear of needles! If you have any other questions, feel free to ask 🙂
Emma x


lisapops
9 months ago

I have set up cladribine UK group on facebook

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