@Cladribine/Mavenclad Year 1. I took my first week or Y1 last week. I don't feel sick or have a headache today but I am absolutely exhausted. My bones feel tired and I'm moving around in slow motion. Did anyone experience this in the week after your first round? I'm working from home but it is taking a herculean strength of mind. I've had interferons and dopamine years ago, azathiapron for 8 years and then 4 months of Tysabri (until I had an allergic reaction). All this to say, this isnt my first treatment experience but this one seems to have wiped me out. Is it just me or are there any other kindred spirits out there? I'd be really grateful for any shared experience and also experience of managing work through treatment weeks. on Shift.ms

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@PoppyJo

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Cladribine/Mavenclad Year 1. I took my first week or Y1 last week. I don't feel sick or have a headache today but I am absolutely exhausted. My bones feel tired and I'm moving around in slow motion. Did anyone experience this in the week after your first round? I'm working from home but it is taking a herculean strength of mind. I've had interferons and dopamine years ago, azathiapron for 8 years and then 4 months of Tysabri (until I had an allergic reaction). All this to say, this isnt my first treatment experience but this one seems to have wiped me out. Is it just me or are there any other kindred spirits out there? I'd be really grateful for any shared experience and also experience of managing work through treatment weeks.

First posted on the Shift.ms app

@PoppyJo

Not dopamine! Copaxone

23 Feb 2026 13:10

@ReginaGBeach

Yep, this sounds like Many peoples experience. Drinking lots of water, reducing any non essential activities and being kind to yourself can help. Bone pain seems to be a particularly difficult side effect. Many people also see a resurgence of fatigue weeks 16-20

23 Feb 2026 16:04