The Edinburgh Centre for Multiple Sclerosis Research is dedicated to unravelling the biological mechanisms that underlie MS and to developing new therapies for its treatment.
An important aspect of the work in the centre is the use of zebrafish as a laboratory model. Using cutting edge microscopy in zebrafish one can now directly observe demyelination (the cause of the symptoms of MS) and remyelination (repair) as they occur in a living animal, which is providing new insights into key biological events of relevance to MS.
Zebrafish are also an ideal system for rapid, cost effective drug discovery screens, and new clinical trials based on work carried out in zebrafish are already in progress. We aim to identify drug-like molecules that can enhance myelin repair in zebrafish, and ultimately translate our findings into new clinical trials for the treatment of MS.
This award will help support PhD students during such important studies.
So that's Dave and Karen's story, we want to hear about yours. Log in or register to share your experiences in our forum.