Good morning all. I have done a bit of a search on Shift.ms for Tizanidine and it doesn't appear to crop up that much. I have been on the starting dose of 2mg daily for a month and to be honest it has not helped. In fact I would say things have got worse. The fatigue is noticeably worse. It's not just physical now, its mental as well. I don't feel hungry any more. I suspect there is some dizziness to, but since I am probably going to get a diagnosis of Ménière’s, this is not unexpected. It is difficult to say what has made it worse. Any one else on Tizanidine? What has been your experience? Is a month no enough to let all the side effects settle down, if they are going to? I am at the point where I need to get my prescription renewed and I am feeling like there is little point. Why take something that doesn't seem to help and in fact is probably making the MS worse. All the best. Paul