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@crussell 

Last reply

crussell

Positive for jc virus

Hello, I am in the process of getting on tysabri and my blood work show I am positive for jc virus. I am hopeful that she will still consider me I am unsure of how to feel as I have hopes with this medication and dont want to go through another relapse even when my mri show no new lesions. Any thoughts suggestion and understanding of the jc virus is appreciated
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@wjgregg
@wjgregg
 

Good morning @crussel, I am on Tysabri too. When I first began, over two years ago, I was JC-. However, on my last blood test, I had switched to JC+. No-one knows why, or how, we become JC+ by the way. All is not lost for you, and I. My MS nurse told me, when I got the news, that when she started off, a JC+ result meant an immediate cessation of Tysabri. No longer. Things have moved on so much. Your doctor should have a percentage chart, correlating your titre level with your percentage risk of PML. If you have been given a booklet from the manufacturers of Tysabri then it is all set out at the back of the booklet. Having considered the percentage risk, it is a matter for you (and your doctor, I suppose) whether you proceed. If you decide to go ahead then you will be very carefully monitored. The whole JC+ thing is a well-known risk. All the medical staff are alive to it. Tysabri is a very effective DMT. I, certainly, have no qualms about recommending it. Good luck with whatever you decide to do. Best wishes, Jon

@poorUserNameChoice
@poorUserNameChoice
 

hey - just for more info... i've been on tysabri for like, 12 years. I've been JC+ for at least the past few years... levels are checked regularly for increase/fluctuation, but I doubt that a pos/neg test result will preclude you from this treatment. Best of luck!