I am supposed to be moving to Ocrevus soon.
I have 1.44 JSV antibodies and the docs here are scared that I will get PML.
My 2 years on Natalizumab (Tysabri) is up on 2 Oct 2020 and they want me off Natalizumab really soon.
My problem is that I am allergic to many medicines and had 5 weeks of incredibly intense nausea upon starting the Natalizumab. This is resulting in me being scared to change medicines despite the supposed 1 in 500 chance of me getting PML.
I also have another major medical issue – Ehlers-Danlos Syndrome (Classical) which is a connective tissue disorder which means I dislocate joints and am prone to allergies (among other things).
I would appreciate any advice regarding thoughts on what you would do if you were me, and also stories on how things were for you when you changed.
Thanks in advance.