Last reply 3 weeks ago
Mavenclad Vs. Tecfidera

Hello all!

This is my first time posting, I am considering switching from tecfidera to Mavenclad. This just became a thought recently & switching a drug that is working for me is a tough decision. I am looking to possibly switch due to flushing, it is very hard to manage with work etc. After meeting with my Nurse Practioner she had suggested Mavenclad & am wondering if anyone can give me some insight.

Thank you,

Jami D

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1 year ago

@jami, Mavenclad was originally successfully trialled sometime ago under its original name of Cladribine. A couple of cases of cancer in the trial participants caused a stop to the development.

It’s only been recently that the trial data has been re-analysed, with Cladribine being absolved as the cause of the cancer. It has been used “off-label” with successful results.

More details here :-

6 months ago

Hey Jami, I’m new to these forums and was quite happy to see this post because I’m in exactly the same position! I have been on Tecfidera for three years but after a recent relapse my neurologist has suggested I switch to Mavenclad. Did you switch, and how did you find it?

I also had terrible flushing with Tecfidera until I started taking a daily aspirin, and that stopped it almost totally.

4 months ago

Hey @systemerror

I’ve since switched to Ocrevus, after my first infusion all is well! Tecfideras side effects were way too much to handle – also found the Asprin very hard on my stomach. Hope all is well!

3 weeks ago

I am on tecfidera and have been on 6 years now and thinking of changing to mavenclad, as my neurologist told me a bit this new drug ..I’m thinking of switching

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