Hello All 🙂 Well where do I start... just a bit of history: I was diagnosed with RRMS at the age of 15 Initially rejected DMDs as I was convinced that I was fine and everyone was wrong...........anyway fast forward to today (36 years old).. I have had all following meds till failure: 1) Rebiff44: 3.5 years 2)Avonex: 6 Months 3) Mytox: 2 years 4) Tysabri: 7 years ,84 infusions... JC Povitive Jan 14' 5) Gilenia 5 years Had a severe relapse early May 2019 pumped with two courses of methylprednisolone a 3 day & followed by a 5 day course. As I have severe RR MS, progressed to EDSS 6.5 and Gilenia failed after five years I have now been offered AHSCT. I have already seen my haematologist and in a real pickle. Sorry for all the history .... Has anyone been through AHSCT, *how did it effect you? *what were the pros and cons? *what was your edss before & after? *in hindsight would you do it again? *any other words of wisdom? ;-) THANK YOU EVER SO MUCH IN ADVANCE !!! Sam