Hi all. Does anyone have any experiences of taking Amantadine for MS fatigue. I am currently taking modafinil x 2 100g first thing each day but still suffer from chronic fatigue in the afternoons. MS Nurse has recommended switching to Amantadine. I’m happy to switch but reluctant to give up modafinil as it does help me get passed the fatigue hump after wakening in the morning even if the fatigue returns later in the day.