Reply To: I can’t move.

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b-o-b
3 weeks ago

@jayjay10

I mean, maybe 10/15 years ago when we only had CRAB drugs (injectables) with only like a little 30% fewer relapses compared to placebo and no evident impact on disability progression, I could have (maybe) understand (a little bit) some neurologists that wanted to go for ‘watchful waiting’. But in 2020? Noway. We know that time is brain and we have high efficacy DMTs that can make you free of relapses or almost (at least 70–80% fewer relapses than placebo, and more). Just have a look on what you can get with some monoclonal antibodies like ocrelizumab after rebaseline at three months, like no more T2 lesions at all (and yes it’s come with side effects but MS is a bad disease): https://www.ocrevus.com/content/dam/gene/ocrevus/hcp/images/charts-reductions-lesion-activity-two-desktop.png