Hi @caole-ann_scott, I can somewhat sympathise. I have experienced worsening, and also new sensations (still in the same area) and have repeatedly been told the same. In fact, I am at the stage now where I don’t bother to report new things/or ask for advice, as the conversations are circular. The way I see it is to keep taking the meds, and rely on the fact that the overall outcome won’t change just because I report it. Does that make sense?